From Professor Kiyokazu Nakajima, MD, PhD, FACS

Research and Development of Minimally Invasive Medical Devices by Industry-Academia-Government Collaboration

At research and development (R&D) of medical devices, it is indispensable to have a substantial collaboration of clinicians who can extract and send out the problems and/or unmet needs encounter in their clinical practice, manufacturing companies and sales company with the ability to solve the problems/needs and bring the products into the world and other experts in intellectual property or medical device regulations. It is inefficient to launch a team each time we start a new R&D, the know-hows we obtained would not accumulate. R&D platform or R&D complex is thus required to function sustainably.

In 2008, we started as a small research group called “ENGINE” within the Department of Gastroenterological Surgery at Osaka University for the purpose of pursuing innovative R&D of medical devices for minimally invasive diagnosis and treatment. ENGINE stands for Endeavour for Next Generation of INterventional Endoscopy; it represents our strong intention to pioneer the next generation of ultra-minimally invasive therapeutic field through R&D of medical devices. Although it was a small industry-academia collaboration project of only 6 companies to start with, we adapted the epochal “open innovation” community system and performed many challenging R&Ds in medical devices. Four years later, in 2012, our group grew up as Department of Next Generation Endoscopic Intervention at Osaka University with 10 companies participating. Supported by more doctors and more companies, our department is now functioning as a unique R&D “platform” with over 20 companies and over 50 supporting clinicians on and off Osaka University.

Our department sent out over 10 medical devices so far and made incomparable achievements as a medical device R&D consortium lead by academia. Among these achievements include some nationwide top selling products used in operating rooms and/or endoscope suites. We hold our position as joint research group and share our research results and have applied for over 100 joint patents. In order not to complete R&D of medical devices as just manufacturing, we also have a mission to work on education in human resource development and scientific activities as part of important duty of being a department of University.

Hope you come back to find our latest work!

特任教授 中島 清一

Kiyokazu Nakajima, MD, PhD, FACS
Professor

Department of Next Generation Endoscopic Intervention (Project ENGINE)
Osaka University Graduate School of Medicine, Osaka, Japan

Department of Surgery, Osaka University Graduate School of Medicine, Osaka, Japan

1992
M.D., Osaka University Medical School
1999
Ph.D., Osaka University Graduate School of Medicine
2001
Postdoctoral Associate in Surgery, Department of Surgery,
Weill Medical College of Cornell University, New York, NY, USA
2004
Chief, Section of Colon and Rectal Surgery, Osaka Rosai Hospital
2006
Assistant Professor of Surgery, Department of Surgery, Osaka University Graduate School of Medicine
2010
Lecturer, Osaka University Medical School
2012
Associate Professor, Department of Surgery, Osaka University Graduate School of Medicine
2012
Professor, Department of Next Generation Endoscopic Intervention, Osaka University Graduate School of Medicine

Professional Organizations and Societies

Japan Surgical Society (Board Certified Surgeon, Board Certified Supervisory Surgeon)
Japanese Society of Gastroenterological Surgery (Council, Board Certified Surgeon, Board Certified Supervisory Surgeon, Board Certified Surgical Oncologist)
Japan Society for Endoscopic Surgery (Council, Laparoscopic Skill Certification, Medical Engineering Collaboration Committee Advisor)
Japanese Board of Cancer Therapy (Certified Instructor, Board Certified Cancer Therapist)
Japanese Society of Gastroenterology (Board Certified Gastroenterologist)
American College of Surgeons, Fellow (FASC)
Society of American Gastrointestinal and Endoscopic Surgery (SAGES)(Member)
European Association for Endoscopic Surgery (International member)
Endoscopic and Laparoscopic Surgeons of Asia (Vice Chairman of Asian Innovation Committee)
World Endoscopy Organization (Surgical Endoscopic Committee member)
Japanese Gastric Cancer Association, The Japan Esophageal Society, The Japan Society of Coloproctology, Japan Surgical Association, Japan Gastroenterological Endoscopic Society, J-CASE (Faculty, Future Committee), Japan TANKO Society (Council), Japan LECS (Council), Kinki Surgical Association (Council), The Kinki Society for Endoscopic Surgery (Faculty), Japanese Society of Medical Instrumentation, Japan Medical Association Certified Occupational Physician

Area of Expertise

  • 1. Gastroenterological Surgery
  • 2. Minimally Invasive Surgery
  • 3. Functional Gastrointestinal Diseases and Motility Disorders
  • 4. Inflammatory Bowel Diseases (Crohn’s Disease, Ulcerative Colitis)
  • 5. Surgical Oncology especially in Gastrointestinal Stromal Tumors
  • 6. Minimally Invasive Endoscopic Treatments and Related Medical Devices
  • 7. Education, especially in Effective Endoscopic Surgery Training
  • 8. Human Resource Development for Medical Device R&D
  • 9. R&D of Medical Devices for Universal Health Coverage

Achievements (as of April 1, 2020)

Publications
32 English papers (including 19 original articles), 51 Japanese papers, 7 English Surgical Text Books, 15 Japanese Medical Text Books
Conference Presentations
329 talks as main speaker (221 domestic, 108 international meetings)
Intellectual Property
Patent: 115 applications, 30 Patent registrations (5 in US, 5 in CN and 4 in EPC)
Design Rights: 18 registrations
Trademarks: 2 registrations
Honors
2009 Crystal Award, DDW, USA
2013 MEDTEC Innovation Award, Challenge Award
2013 MONOZUKURI Nippon Grand Award, the Special Prize, The Ministry of Economy, Trade and Industry (METI)
2014 Risona Foundation for Small and Medium Enterprise Promotion Award 2014
2014 Osaka University Presidential Award 2014
2018 Ogami Award, Japan Society for Endoscopic Surgery
2019 Ozawa Award, Osaka University Graduate School of Medicine, Department of Surgery (Kyusenkai)
Competitive Research Funds :
Ministry of Economy, Trade and Industry; Ministry of Education, Culture, Sports, Science and Technology; Ministry of Health, Labor and Welfare; Japanese Society for Promotion of Sciences; National Federation of Small Business Associations; Private Grants and other International Subsidies